Smoking and vaporized flower
Combusted flower (joints, pipes, bongs) or dry-herb vaporized flower delivers THC through the lungs into the bloodstream within seconds. Onset is fast: 2-5 minutes. Peak hits at 15-30 minutes. Duration is typically 1-3 hours, depending on dose and tolerance. Inhaled methods are the most controllable for tolerance-building because you feel the effect almost immediately and can stop redosing once you're where you want to be.
Cartridges and vape pens
510-thread cartridges and all-in-one disposables vaporize cannabis distillate or live resin. Onset is similar to smoked flower (2-5 minutes), but the effect is often described as more uniform — distillate is processed for high purity. Live-resin carts retain more terpenes for richer flavor. Sessions last 1-2 hours. Hardware quality matters: a cart that pulls clean and fires every time is worth a few dollars more.
Edibles — gummies, chocolates, drinks
Oral cannabis must pass through the liver, which converts THC to 11-hydroxy-THC — a longer-lasting, often-stronger metabolite. Onset is slow: 60-90 minutes (sometimes 2 hours on a full stomach). Peak hits at 2-3 hours. Duration is 4-8 hours. The dosing mistake new users make is taking more before the first dose hits. Start at 2.5-5 mg and wait the full 90 minutes minimum.
Sublingual tinctures
Drops placed under the tongue absorb through oral mucosa, bypassing the liver. Onset is faster than swallowed edibles: 15-45 minutes. Duration is shorter than edibles too: 2-4 hours. Sublinguals are useful for predictable, discreet dosing without the slow burn of digestion.
Topicals — non-intoxicating
Balms, lotions, and patches deliver cannabinoids through the skin for localized effects — sore muscles, joint stiffness, skin conditions. Topicals do not produce a head-high because cannabinoids don't pass into the bloodstream at intoxicating concentrations through unbroken skin. Onset is gradual; effects build over 30-60 minutes and last 2-4 hours.
- Cannabis pharmacokinetics: comparative routes of administration — PubMed Central / NIH
- Effects of route of administration on cannabis intoxication — National Center for Biotechnology Information
